2024
Retinoids Molecular Probes by Late-stage Azide Insertion – Functional Tools to Decrypt Retinoid Metabolism
Jessica Coulleray, Alexia Kindler, Mohamad Rima, Héloïse Cahuzac, Natacha Rochel, Guilhem Chaubet, Wojciech Krezel, Alain Wagner, ChembioChem 2024
Doi :10.1002/cbic.202300689
SEC-MS in denaturing conditions (dSEC-MS) for in-depth analysis of rebridged monoclonal antibody-based formats
Rania Benazza, Ilias Koutsopetras, Valentine Vaur, Guilhem Chaubet, Oscar Hernandez-Alba, Sarah Cianférani, Talanta 2024.
DOI : 10.1016/j.talanta.2024.125727
Rania Benazza, Ilias Koutsopetras, Valentine Vaur, Guilhem Chaubet, Oscar Hernandez-Alba, Sarah Cianférani, Talanta 2024.
DOI : 10.1016/j.talanta.2024.125727
Targeted delivery of immune-stimulating bispecific RNA, inducing apoptosis and anti-tumor immunity in cancer cells
Tony Rady, Stéphane Erb, Safia Deddouche-Grass, Renaud Morales, Guilhem Chaubet, Sarah Cianférani, Nicolas Basse, Alain Wagner, ISCIENCE, 2024
DOI : 10.1016/j.isci.2024.109068
Tony Rady, Stéphane Erb, Safia Deddouche-Grass, Renaud Morales, Guilhem Chaubet, Sarah Cianférani, Nicolas Basse, Alain Wagner, ISCIENCE, 2024
DOI : 10.1016/j.isci.2024.109068
Drug upgrade: A complete methodology from old drug to new chemical entities using Nematic Protein Organization Technique
Judith Eschbach, Alain Wagner, Corinne Beahr, Akkiz Bekel, Anne-Sophie Korganow, Angelique Quartier, Jean-Christophe Peter, Pierre Eftekhari, Drug Dev Res. 2024
DOI : 10.1002/ddr.22151
Judith Eschbach, Alain Wagner, Corinne Beahr, Akkiz Bekel, Anne-Sophie Korganow, Angelique Quartier, Jean-Christophe Peter, Pierre Eftekhari, Drug Dev Res. 2024
DOI : 10.1002/ddr.22151
2023
Site-Selective Protein Conjugation by a Multicomponent Ugi Reaction
Ilias Koutsopetras, Valentine Vaur, Rania Benazza, Hélène Diemer, Charlotte Sornay, Yağmur Ersoy, Léa Rochet, Carmen Longo, Oscar Hernandez-Alba, Stéphane Erb, Alexandre Detappe, Arne Skerra, Alain Wagner, Sarah Cianferani, Guilhem Chaubet, Chem. Eur. J.2023
DOI : 10.1002/chem.202303242
Ilias Koutsopetras, Valentine Vaur, Rania Benazza, Hélène Diemer, Charlotte Sornay, Yağmur Ersoy, Léa Rochet, Carmen Longo, Oscar Hernandez-Alba, Stéphane Erb, Alexandre Detappe, Arne Skerra, Alain Wagner, Sarah Cianferani, Guilhem Chaubet, Chem. Eur. J.2023
DOI : 10.1002/chem.202303242
Reinvestigation of the Automated Synthesis of Stoichiometrically Conjugated Antibodies to Access High Molecular Weight Payloads and Multiplexed Conjugation via an In-Solution Trans-Tagging Process.
Victor Lehot, Ondřej Lidický, Julien Most, Stéphane Erb, Igor Dovgan, Artem Osypenko, Oleksandr Koniev, Sergii Kolodych, Lenka Kotrchová, Guilhem Chaubet, Sarah Cianférani, Tomáš Etrych, and Alain Wagner*; ACS Omega 2023
DOI : 10.1021/acsomega.3c05206
Victor Lehot, Ondřej Lidický, Julien Most, Stéphane Erb, Igor Dovgan, Artem Osypenko, Oleksandr Koniev, Sergii Kolodych, Lenka Kotrchová, Guilhem Chaubet, Sarah Cianférani, Tomáš Etrych, and Alain Wagner*; ACS Omega 2023
DOI : 10.1021/acsomega.3c05206
Cysteine-Cysteine Cross-Conjugation of both Peptides andProteins with a Bifunctional Hypervalent Iodine-Electrophilic Reagent
Ilias Koutsopetras, Abhaya Kumar Mishra, Rania Benazza,Oscar Hernandez-Alba, Sarah Cianférani, Guilhem Chaubet, Stefano Nicolai, and Jerome Waser; Chem. Eur. J. 2023, e202302689
DOI : 10.1002/chem.202302689
Ilias Koutsopetras, Abhaya Kumar Mishra, Rania Benazza,Oscar Hernandez-Alba, Sarah Cianférani, Guilhem Chaubet, Stefano Nicolai, and Jerome Waser; Chem. Eur. J. 2023, e202302689
DOI : 10.1002/chem.202302689
Microfluidic Droplet Stabilization via SPAAC Promoted Antibody Conjugation at the Water/Oil Interfaceit.
Robin Dufossez, Marie-Pierre Krafft, Sylvain Ursuegui, Michel Mosser, Safae Mouftakhir, Ketty Pernod, Guilhem Chaubet, Michael Ryckelynck, Alain Wagner;
DOI: 10.1021/acsami.3c10655
Robin Dufossez, Marie-Pierre Krafft, Sylvain Ursuegui, Michel Mosser, Safae Mouftakhir, Ketty Pernod, Guilhem Chaubet, Michael Ryckelynck, Alain Wagner;
DOI: 10.1021/acsami.3c10655
Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles
Victor Lehot , Patrick Neuberg, Manon Ripoll, François Daubeuf, Stéphane Erb, Igor Dovgan, Sylvain Ursuegui, Sarah Cianférani, Antoine Kichler , Guilhem Chaubet and Alain Wagner; Pharmaceutics 2023, 15, 1643.
Doi : 10.3390/pharmaceutics15061643
Victor Lehot , Patrick Neuberg, Manon Ripoll, François Daubeuf, Stéphane Erb, Igor Dovgan, Sylvain Ursuegui, Sarah Cianférani, Antoine Kichler , Guilhem Chaubet and Alain Wagner; Pharmaceutics 2023, 15, 1643.
Doi : 10.3390/pharmaceutics15061643
Droplet Surface Immunoassay by Relocation (D-SIRe) for High-Throughput Analysis of Cytosolic Proteins at the Single-Cell Level
Robin Dufossez, Sylvain Ursuegui, Stephanie Baudrey, Ketty Pernod, Safae Mouftakhir, Mustapha Oulad-Abdelghani, Michel Mosser, Guilhem Chaubet, Michael Ryckelynck, Alain Wagner; Anal. Chem. 2023. 95, 9, 4470-4478.
Doi: 10.1021/acs.analchem.2c05168
Robin Dufossez, Sylvain Ursuegui, Stephanie Baudrey, Ketty Pernod, Safae Mouftakhir, Mustapha Oulad-Abdelghani, Michel Mosser, Guilhem Chaubet, Michael Ryckelynck, Alain Wagner; Anal. Chem. 2023. 95, 9, 4470-4478.
Doi: 10.1021/acs.analchem.2c05168
2022
A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity
Tony Rady, Lorenzo Turelli, Marc Nothisen, Elisabetta Tobaldi, Stéphane Erb, Fabien Thoreau, Oscar Hernandez-Alba, Sarah Cianferani, François Daubeuf, Alain Wagner, Guilhem Chaubet; Bioconjugate. Chem. 2022. 33, 10, 1860-1866.
Doi: 10.1021/acs.bioconjchem.2c00314
Tony Rady, Lorenzo Turelli, Marc Nothisen, Elisabetta Tobaldi, Stéphane Erb, Fabien Thoreau, Oscar Hernandez-Alba, Sarah Cianferani, François Daubeuf, Alain Wagner, Guilhem Chaubet; Bioconjugate. Chem. 2022. 33, 10, 1860-1866.
Doi: 10.1021/acs.bioconjchem.2c00314
An overview of chemo- and site-selectivity aspects in the chemical conjugation of proteins
Charlotte Sornay, Valentine Vaur, Alain Wagner, Guilhem Chaubet; R. Soc. Open. Sci. 2022. 9, 211563.
Doi: 10.1098/rsos.211563
Charlotte Sornay, Valentine Vaur, Alain Wagner, Guilhem Chaubet; R. Soc. Open. Sci. 2022. 9, 211563.
Doi: 10.1098/rsos.211563
2021
Bicyclo[6.1.0]nonyne carboxylic acid for the production of stable molecular probes
Tony Rady, Michel Mosser, Marc Nothisen, Stephane Erb, Igor Dovgan, Sarah Cianférani, Alain Wagner, Guilhem Chaubet; RSC. Adv. 2021. 11, 36777-36780.
Doi: 10.1039/D1RA07905K
Tony Rady, Michel Mosser, Marc Nothisen, Stephane Erb, Igor Dovgan, Sarah Cianférani, Alain Wagner, Guilhem Chaubet; RSC. Adv. 2021. 11, 36777-36780.
Doi: 10.1039/D1RA07905K
Plasma induced acceleration and selectivity in strain-promoted azide-alkyne cycloadditions
David Warther, Enes Dursun, Marion Recher, Sylvain Ursuegui, Michel Mosser, Joanna Sobska, Wojciech Krezel, Guilhem Chaubet, Alain Wagner; Org. Biomol. Chem. 2021. 19, 5063-5067.
Doi: 10.1039/D1OB00529D
David Warther, Enes Dursun, Marion Recher, Sylvain Ursuegui, Michel Mosser, Joanna Sobska, Wojciech Krezel, Guilhem Chaubet, Alain Wagner; Org. Biomol. Chem. 2021. 19, 5063-5067.
Doi: 10.1039/D1OB00529D
Non-specific interactions of antibody-oligonucleotide conjugates with living cells
Victor Lehot, Isabelle Kuhn, Marc Nothisen, Stéphane Erb, Sergii Kolodych, Sarah Cianférani, Guilhem Chaubet, Alain Wagner; Sci. Rep. 2021. 11, 5881.
Doi: 10.1038/s41598-021-85352-w
Victor Lehot, Isabelle Kuhn, Marc Nothisen, Stéphane Erb, Sergii Kolodych, Sarah Cianférani, Guilhem Chaubet, Alain Wagner; Sci. Rep. 2021. 11, 5881.
Doi: 10.1038/s41598-021-85352-w
2020
Maniindole, an indole derivative from the roots of Anonidium manii and combined antischistosomal and enzymatic activities
Josette Linda Toussi Matchi, Diderot Tchamo Noungoue, Isabelle Kuhn Jérôme Boissier, Jean Claude Tchouankeu, Marc Nothisen, Guilhem Chaubet, Delphine Garnier, Sylvain Ursuegui, Silvère Augustin, Alain Wagner; Nat. Prod. Res. 2020. 1-9.
Doi: 10.1080/14786419.2020.1824227
Josette Linda Toussi Matchi, Diderot Tchamo Noungoue, Isabelle Kuhn Jérôme Boissier, Jean Claude Tchouankeu, Marc Nothisen, Guilhem Chaubet, Delphine Garnier, Sylvain Ursuegui, Silvère Augustin, Alain Wagner; Nat. Prod. Res. 2020. 1-9.
Doi: 10.1080/14786419.2020.1824227
Dual Gene Delivery Reagents From Antiproliferative Alkylphospholipids for Combined Antitumor Therapy
Boris Gaillard, Jean-Serge Remy, Françoise Pons, Luc Lebeau; Front. Chem. 2020. 8, 581260.
Doi: 10.3389/fchem.2020.581260
Boris Gaillard, Jean-Serge Remy, Françoise Pons, Luc Lebeau; Front. Chem. 2020. 8, 581260.
Doi: 10.3389/fchem.2020.581260
Synthesis and Evaluation of Antitumor Alkylphospholipid Prodrugs
Boris Gaillard, Jean-Serge Remy, Françoise Pons, Luc Lebeau; Pharm. Res. 2020. 37, 6, 106.
Doi.org/10.1007/s11095-020-02830-y
Boris Gaillard, Jean-Serge Remy, Françoise Pons, Luc Lebeau; Pharm. Res. 2020. 37, 6, 106.
Doi.org/10.1007/s11095-020-02830-y
Investigating Ugi / Passerini multicomponent reactions for the Site‐Selective Conjugation of Native Trastuzumab
Charlotte Sornay, Steve Hessmann, Stéphane Erb, Igor Dovgan, Anthony Ehkirch, Thomas Botzanowski, Sarah Cianférani, Alain Wagner, Guilhem Chaubet; Chem. Eur. J. 2020. 26, 61, 13797-13805.
Doi:10.1002/chem.202002432
Charlotte Sornay, Steve Hessmann, Stéphane Erb, Igor Dovgan, Anthony Ehkirch, Thomas Botzanowski, Sarah Cianférani, Alain Wagner, Guilhem Chaubet; Chem. Eur. J. 2020. 26, 61, 13797-13805.
Doi:10.1002/chem.202002432
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On the use of DNA as a linker in antibody-drug conjugates: synthesis, stability and in vitro potency
Igor Dovgan, Anthony Ehkirch, Victor Lehot, Isabelle Kuhn, Oleksandr Koniev, Sergii Kolodych, Alexandre Hentz, Manon Ripoll, Sylvain Ursuegui, Marc Nothisen, Sarah Cianférani, Alain Wagner; Sci. Rep., 2020, 10, 7691.
Doi.org/10.1038/s41598-020-64518-y
Igor Dovgan, Anthony Ehkirch, Victor Lehot, Isabelle Kuhn, Oleksandr Koniev, Sergii Kolodych, Alexandre Hentz, Manon Ripoll, Sylvain Ursuegui, Marc Nothisen, Sarah Cianférani, Alain Wagner; Sci. Rep., 2020, 10, 7691.
Doi.org/10.1038/s41598-020-64518-y
Ethynylation of Cysteine Residues: From Peptides to Proteins in Vitro and in Living Cells
Romain Tessier, Raj Kumar Nandi, Brendan G. Dwyer, Daniel Abegg, Charlotte Sornay, Javier Ceballos, Stephane Erb, Sarah Cianferani, Alain Wagner, Guilhem Chaubet, Alexander Adibekian, Jerome Waser; Angew. Chem. Int. Ed. 2020 , 59 , 10961.
Doi.org/10.1002/anie.202002626
Romain Tessier, Raj Kumar Nandi, Brendan G. Dwyer, Daniel Abegg, Charlotte Sornay, Javier Ceballos, Stephane Erb, Sarah Cianferani, Alain Wagner, Guilhem Chaubet, Alexander Adibekian, Jerome Waser; Angew. Chem. Int. Ed. 2020 , 59 , 10961.
Doi.org/10.1002/anie.202002626
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Automated linkage of proteins and payloads producing monodisperse conjugates
Igor Dovgan, Alexandre Hentz, Oleksandr Koniev, Anthony Ehkirch, Steve Hessmann, Sylvain Ursuegui, Sébastien Delacroix, Margaux Riomet, Frédéric Taran, Sarah Cianférani, Sergii Kolodych, Alain Wagner; Chem. Sci., 2020, 11, 1210-1215.
Doi: 10.1039/C9SC05468E
Igor Dovgan, Alexandre Hentz, Oleksandr Koniev, Anthony Ehkirch, Steve Hessmann, Sylvain Ursuegui, Sébastien Delacroix, Margaux Riomet, Frédéric Taran, Sarah Cianférani, Sergii Kolodych, Alain Wagner; Chem. Sci., 2020, 11, 1210-1215.
Doi: 10.1039/C9SC05468E
2019
Antibody-Oligonucleotide Conjugates as Therapeutic, Imaging, and Detection Agents
Igor Dovgan, Oleksandr Koniev, Sergii Kolodych, Alain Wagner; Bioconjugate Chem., 2019, 30, 10, 2483-2501.
DOI: 10.1021/acs.bioconjchem.9b00306
Igor Dovgan, Oleksandr Koniev, Sergii Kolodych, Alain Wagner; Bioconjugate Chem., 2019, 30, 10, 2483-2501.
DOI: 10.1021/acs.bioconjchem.9b00306
Design and evaluation of ionizable peptide amphiphiles for siRNA delivery.
Patrick Neuberg, Alain Wagner, Jean-Serge Remy, Antoine Kichler; Int. J. Pharmaceut., 2019, 566, 141-148.
DOI: 10.1016/j.ijpharm.2019.05.052
Patrick Neuberg, Alain Wagner, Jean-Serge Remy, Antoine Kichler; Int. J. Pharmaceut., 2019, 566, 141-148.
DOI: 10.1016/j.ijpharm.2019.05.052
Sydnone-based turn-on fluorogenic probes for no-wash protein labeling and in-cell imaging.
Lucie Plougastel, Manas R. Pattanayak, Margaux Riomet, Sarah Bregant, Antoine Sallustrau, Marc Nothisen, Alain Wagner, Davide Audisio, Frédéric Taran; Chem. Commun., 2018, 55, 4582-4585.
DOI: 10.1039/C9CC01458F
Lucie Plougastel, Manas R. Pattanayak, Margaux Riomet, Sarah Bregant, Antoine Sallustrau, Marc Nothisen, Alain Wagner, Davide Audisio, Frédéric Taran; Chem. Commun., 2018, 55, 4582-4585.
DOI: 10.1039/C9CC01458F
2018
Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E-coli YgbP/IspD
Zoljargal Baatarkhuu, Philippe Chaignon, Franck Borel, Jean-Luc Ferrer, Alain Wagner, Myriam Seemann; Scientific Reports, 2018, 8, 17892-17901.
DOI: 10.1038/s41598-018-35586-y038/s41598-018-35586-y :10.1038/s41598-018-35586-y
Zoljargal Baatarkhuu, Philippe Chaignon, Franck Borel, Jean-Luc Ferrer, Alain Wagner, Myriam Seemann; Scientific Reports, 2018, 8, 17892-17901.
DOI: 10.1038/s41598-018-35586-y038/s41598-018-35586-y :10.1038/s41598-018-35586-y
Co-delivery of anti-PLK-1 si RNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing
Manon Ripoll, Marie Pierdant, Patrick Neuberg, Dominique Bagnard, Alain Wagner, Antoine Kichler, Jean-Serge Remy; RSC Advances, 2018, 8, 20758-20763.
DOI: 10.1039/c8ra03375g
Manon Ripoll, Marie Pierdant, Patrick Neuberg, Dominique Bagnard, Alain Wagner, Antoine Kichler, Jean-Serge Remy; RSC Advances, 2018, 8, 20758-20763.
DOI: 10.1039/c8ra03375g
Expedient synthesis of trifunctional oligoethyleneglycol-amine linkers and their use in the preparation of PEG-based branched platforms
Sylvain Ursuegui, Jérémy P. Schneider, Claire Imbs, Florian Lauvoisard, Marta Dudek, Michel Mosser, Alain Wagner; Organic and Biomolecular Chemistry, 2018, 16, 8579-8584.
DOI: 10.1039/c8ob02097c
Sylvain Ursuegui, Jérémy P. Schneider, Claire Imbs, Florian Lauvoisard, Marta Dudek, Michel Mosser, Alain Wagner; Organic and Biomolecular Chemistry, 2018, 16, 8579-8584.
DOI: 10.1039/c8ob02097c
Recent, non-classical, approaches to antibody lysine modification
Guilhem Chaubet, Fabien Thoreau, Alain Wagner; Drug Discovery Today: Technologies, 2018, 30, 21-26.
DOI: 10.1016/j.ddtec.2018.09.002
Guilhem Chaubet, Fabien Thoreau, Alain Wagner; Drug Discovery Today: Technologies, 2018, 30, 21-26.
DOI: 10.1016/j.ddtec.2018.09.002
Reduction Inhibition of dengue virus infection by mannoside glycolipid conjugates
Evelyne Schaeffer, Vincent Flacher, Patrick Neuberg, Astrid Hoste, Adrien Brulefert, Jean-Daniel Fauny, Alain Wagner, Christopher G. Mueller; Antiviral Research, 2018, 154, 116-123.
DOI: 10.1016/j.antiviral.2018.04.005
Evelyne Schaeffer, Vincent Flacher, Patrick Neuberg, Astrid Hoste, Adrien Brulefert, Jean-Daniel Fauny, Alain Wagner, Christopher G. Mueller; Antiviral Research, 2018, 154, 116-123.
DOI: 10.1016/j.antiviral.2018.04.005
Reduction–rebridging strategy for the preparation of ADPN-based antibody–drug conjugates
Oleksandr Koniev, Igor Dovgan, Brigitte Renoux, Anthony Ehkirch, Jitka Eberova, Sarah Cianférani, Sergii Kolodych, Sébastien Papot and Alain Wagner, Med. Chem. Commun., 2018, 9, 5, 827-830.
DOI: 10.1039/C8MD00141C
Oleksandr Koniev, Igor Dovgan, Brigitte Renoux, Anthony Ehkirch, Jitka Eberova, Sarah Cianférani, Sergii Kolodych, Sébastien Papot and Alain Wagner, Med. Chem. Commun., 2018, 9, 5, 827-830.
DOI: 10.1039/C8MD00141C
Arginine-Selective Bioconjugation with 4-Azidophenyl glyoxal: Application to the single and Dual Functionalisation of Native Antibody
Igor Dovgan, Stéphane Erb, Steve Hessman, Sylvain Ursuegui, Chloé Michel, Christian Muller, Guilhem Chaubet, Sarah Cianférani and Alain Wagner, Organic & Biomolecular Chemistry, 2018, 16, 8, 1305-1311.
DOI: 10.1039/C7OB02844J
Igor Dovgan, Stéphane Erb, Steve Hessman, Sylvain Ursuegui, Chloé Michel, Christian Muller, Guilhem Chaubet, Sarah Cianférani and Alain Wagner, Organic & Biomolecular Chemistry, 2018, 16, 8, 1305-1311.
DOI: 10.1039/C7OB02844J
Polydiacetylenic Nanofibers as New siRNA Vehicles for in vitro and in vivo Delivery
E P. Neuberg, I. Hamaidi, D. Danilin, M. Ripoll, V. Lindner, M. Nothisen, A. Wagner, A. Kichler, T. Massfelder and J.-D. Remy, Nanoscale, 2018, 10, 1587-1590.
DOI: 10.1039/C7NR09202D
E P. Neuberg, I. Hamaidi, D. Danilin, M. Ripoll, V. Lindner, M. Nothisen, A. Wagner, A. Kichler, T. Massfelder and J.-D. Remy, Nanoscale, 2018, 10, 1587-1590.
DOI: 10.1039/C7NR09202D
2017
Structural Investigation of Cyclo-dioxo Maleimide Cross-linkers for Acid and Serum Stability
Elisabetta Tobaldi, Igor Dovgan, Michel Mosser, Jean-Michel Becht, Alain Wagner, Organic & Biomolecular Chemistry, 2017, 15, 9305-9310.
DOI: 10.1039/c7ob01757j
Elisabetta Tobaldi, Igor Dovgan, Michel Mosser, Jean-Michel Becht, Alain Wagner, Organic & Biomolecular Chemistry, 2017, 15, 9305-9310.
DOI: 10.1039/c7ob01757j
Discovery of New Click and Release Reactions by Screening of Mesoionics and Cycloalkynes Combinations
Frédéric Taran, Sabrina Bernard, Davide Audisio, Riomet Margaux, Sarah Bregant, Antoine Sallustrau, Lucie Plougastel, Elodie Decuypere, Sandra Gabillet, Ramar Arun Kumar, Jijy Elyian, Minh Nguyet Trinh, Oleksandr Koniev, Alain Wagner, Sergii Kolodych, Angewandte Chemie International Edition, 2017, 56, 49, 15612–15616.
DOI: 10.1002/anie.201708790
Frédéric Taran, Sabrina Bernard, Davide Audisio, Riomet Margaux, Sarah Bregant, Antoine Sallustrau, Lucie Plougastel, Elodie Decuypere, Sandra Gabillet, Ramar Arun Kumar, Jijy Elyian, Minh Nguyet Trinh, Oleksandr Koniev, Alain Wagner, Sergii Kolodych, Angewandte Chemie International Edition, 2017, 56, 49, 15612–15616.
DOI: 10.1002/anie.201708790
Development and evaluation of β-galactosidase-sensitive antibody-drug conjugates
Sergii Kolodych, Chloé Michel, Sébastien Delacroix, Oleksandr Koniev, Anthony Ehkirch, Jitka Eberova, Sarah Cianférani, Brigitte Renoux, Wojciech Krezel, Pauline Poinot, Christian D. Muller, Sébastien Papot, Alain Wagner, European Journal of Medicinal Chemistry, 2017, 142, 376-382.
DOI: 10.1016/j.ejmech.2017.08.008
Sergii Kolodych, Chloé Michel, Sébastien Delacroix, Oleksandr Koniev, Anthony Ehkirch, Jitka Eberova, Sarah Cianférani, Brigitte Renoux, Wojciech Krezel, Pauline Poinot, Christian D. Muller, Sébastien Papot, Alain Wagner, European Journal of Medicinal Chemistry, 2017, 142, 376-382.
DOI: 10.1016/j.ejmech.2017.08.008
An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin
Sylvain Ursuegui, Marion Recher, Wojciech Krężel, Alain Wagner. Nature Comm., 2017, 8, 15242.
DOI: 10.1038/ncomms15242
Sylvain Ursuegui, Marion Recher, Wojciech Krężel, Alain Wagner. Nature Comm., 2017, 8, 15242.
DOI: 10.1038/ncomms15242
Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy.
Igor Dovgan, Sylvain Ursuegui, Stéphane Erb, Chloé Michel, Sergii Kolodych, Sarah Cianférani, Alain Wagner. Bioconjugate Chem., 2017, 28, 5, 1452-1457.
DOI: 10.1021/acs.bioconjchem.7b00141
Igor Dovgan, Sylvain Ursuegui, Stéphane Erb, Chloé Michel, Sergii Kolodych, Sarah Cianférani, Alain Wagner. Bioconjugate Chem., 2017, 28, 5, 1452-1457.
DOI: 10.1021/acs.bioconjchem.7b00141
2016
pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery.
Manon Ripoll, Patrick Neuberg, Antoine Kichler, Nassera Tounsi, Alain Wagner, Jean-Serge Remy. ACS Appl Mater Interfaces, 2016, 8, 45, 30665–30670.
DOI: 10.1021/acsami.6b09365
Manon Ripoll, Patrick Neuberg, Antoine Kichler, Nassera Tounsi, Alain Wagner, Jean-Serge Remy. ACS Appl Mater Interfaces, 2016, 8, 45, 30665–30670.
DOI: 10.1021/acsami.6b09365
Copper-free click chemistry for microdroplet's W/O interface engineering.
Sylvain Ursuegui, Michel Mosser, Alain Wagner. RSC Advances, 2016, 6, 97, 94942 – 94948.
DOI: 10.1039/C6RA20385J
Sylvain Ursuegui, Michel Mosser, Alain Wagner. RSC Advances, 2016, 6, 97, 94942 – 94948.
DOI: 10.1039/C6RA20385J
Ultrafast Click Chemistry with Fluorosydnones.
Hui Liu, Davide Audisio, Lucie Plougastel, Elodie Decuypere, David-Alexandre Buisson, Oleksandr Koniev, Sergii Kolodych, Alain Wagner, Mourad Elhabiri, Anna Krzyczmonik, Sarita Forsback, Olof Solin, Véronique Gouverneur, Frédéric Taran. Angewandte Chemie Int. Ed., 2016, 55, 39, 12073 –12077.
Doi: 10.1002/anie.201606495
Hui Liu, Davide Audisio, Lucie Plougastel, Elodie Decuypere, David-Alexandre Buisson, Oleksandr Koniev, Sergii Kolodych, Alain Wagner, Mourad Elhabiri, Anna Krzyczmonik, Sarita Forsback, Olof Solin, Véronique Gouverneur, Frédéric Taran. Angewandte Chemie Int. Ed., 2016, 55, 39, 12073 –12077.
Doi: 10.1002/anie.201606495
2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation.
Igor Dovgan, Sergii Kolodych, Oleksandr Koniev, Alain Wagner. Nature Scientific Report, 2016, 6, 1, 30835-30840.
DOI: 10.1038/srep30835
Igor Dovgan, Sergii Kolodych, Oleksandr Koniev, Alain Wagner. Nature Scientific Report, 2016, 6, 1, 30835-30840.
DOI: 10.1038/srep30835
Palladium Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature.
Riyadh Ahmed Atto Al-Shuaeeb, Sergii Kolodych, Oleksandr Koniev, Sébastien Delacroix, Stéphane Erb, Stéphanie Nicolaÿ, Jean-Christophe Cintrat, Jean-Daniel Brion, Sarah Cianférani, Mouâd Alami, Alain Wagner, Samir Messaoudi. Chem. Eur. J., 2016, 22, 32, 11365 – 11370.
DOI: 10.1002/chem.201602277
Riyadh Ahmed Atto Al-Shuaeeb, Sergii Kolodych, Oleksandr Koniev, Sébastien Delacroix, Stéphane Erb, Stéphanie Nicolaÿ, Jean-Christophe Cintrat, Jean-Daniel Brion, Sarah Cianférani, Mouâd Alami, Alain Wagner, Samir Messaoudi. Chem. Eur. J., 2016, 22, 32, 11365 – 11370.
DOI: 10.1002/chem.201602277
From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release.
Sylvain A. Jacques, Geoffray Leriche, Michel Mosser, Marc Nothisen, Christian D. Muller, Jean-Serge Remy, Alain Wagner. Org. Biomol. Chem., 2016, 14, 21, 4794–4803.
DOI: 10.1039/C6OB00846A
Sylvain A. Jacques, Geoffray Leriche, Michel Mosser, Marc Nothisen, Christian D. Muller, Jean-Serge Remy, Alain Wagner. Org. Biomol. Chem., 2016, 14, 21, 4794–4803.
DOI: 10.1039/C6OB00846A
2015
Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation.
Vincent Flacher, Patrick Neuberg, Floriane Point, François Daubeuf, Quentin Muller, David Sigwalt, Jean-Daniel Fauny, Jean-Serge Remy, Nelly Frossard, Alain Wagner, Christophe G. Mueller, Evelyne Schaeffer. ACS Chem. Biol., 2015, 10, 12, 2697–2705.
Doi: 10.1021/acschembio.5b00552
Vincent Flacher, Patrick Neuberg, Floriane Point, François Daubeuf, Quentin Muller, David Sigwalt, Jean-Daniel Fauny, Jean-Serge Remy, Nelly Frossard, Alain Wagner, Christophe G. Mueller, Evelyne Schaeffer. ACS Chem. Biol., 2015, 10, 12, 2697–2705.
Doi: 10.1021/acschembio.5b00552
MAPN: First-in-Class Reagent for kinetically Resolved Thiol-to-Thiol Conjugation
Oleksandr Koniev, Sergii Kolodych, Zoljargal Baatarkhuu, Johann Stojko, Jitka Eberova, Jean-Yves Bonnefoy, Sarah Cianférani, Alain Van Dorsselear, Alain Wagner. Bioconjugate Chem., 2015, 26, 9, 1863–1867.
DOI: 10.1021/acs.bioconjchem.5b00440
Oleksandr Koniev, Sergii Kolodych, Zoljargal Baatarkhuu, Johann Stojko, Jitka Eberova, Jean-Yves Bonnefoy, Sarah Cianférani, Alain Van Dorsselear, Alain Wagner. Bioconjugate Chem., 2015, 26, 9, 1863–1867.
DOI: 10.1021/acs.bioconjchem.5b00440
Spiro Di-orthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release
Geoffray Leriche, Marc Nothisen, Nadège Baumlin, Christian D. Muller, Dominique Bagnard, Jean-Serge Remy, Sylvain A. Jacques, A. Wagner, Bioconjugate Chem., 2015, 26, 8, 1461-1465.
DOI: 10.1021/acs.bioconjchem.5b00280
Geoffray Leriche, Marc Nothisen, Nadège Baumlin, Christian D. Muller, Dominique Bagnard, Jean-Serge Remy, Sylvain A. Jacques, A. Wagner, Bioconjugate Chem., 2015, 26, 8, 1461-1465.
DOI: 10.1021/acs.bioconjchem.5b00280
Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties
Patrick Neuberg, Aurélia Périno, Emmanuelle Morin-Picardat, Nicolas Anton, Zeinab Darwich, Denis Weltin, Yves Mely, Andrey S. Klymchenko, Jean-Serge Remy, Alain Wagner. Chem. Commun., 2015, 51, 58, 11595-11598.
DOI: 10.1039/c5cc03820k
Patrick Neuberg, Aurélia Périno, Emmanuelle Morin-Picardat, Nicolas Anton, Zeinab Darwich, Denis Weltin, Yves Mely, Andrey S. Klymchenko, Jean-Serge Remy, Alain Wagner. Chem. Commun., 2015, 51, 58, 11595-11598.
DOI: 10.1039/c5cc03820k
Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation
Oleksandr Koniev, Alain Wagner. Chem. Soc. Rev., 2015, 44, 5495-5551.
Doi: 10.1039/C5CS00048C
Oleksandr Koniev, Alain Wagner. Chem. Soc. Rev., 2015, 44, 5495-5551.
Doi: 10.1039/C5CS00048C
Discovery of potent inhibitors of Schistosoma mansoni NAD+ catabolizing enzyme
Sylvain A. Jacques, Isabelle Kuhn, Oleksandr Koniev, Francis Schuber, Frances E. Lund, Alain Wagner, Hélène Muller-Steffner, Esther Kellenberger, J. Med. Chem., 2015, 58, 8, 3582–3592.
DOI: 10.1021/acs.jmedchem.5b00203
Sylvain A. Jacques, Isabelle Kuhn, Oleksandr Koniev, Francis Schuber, Frances E. Lund, Alain Wagner, Hélène Muller-Steffner, Esther Kellenberger, J. Med. Chem., 2015, 58, 8, 3582–3592.
DOI: 10.1021/acs.jmedchem.5b00203
CBTF: New Amine-to-Thiol Coupling Reagent for Preparation of Antibody Conjugates with Increased Plasma Stability
Sergii Kolodych, Oleksandr Koniev, Zoljargal Baatarkhuu, Jean-Yves Bonnefoy, François Debaene, Sarah Cianférani, Alain Van Dorsselaer, Alain Wagner. Bioconjugate Chem. 2015, 26, 2, 197–200.
Doi: 10.1021/bc500610g
Sergii Kolodych, Oleksandr Koniev, Zoljargal Baatarkhuu, Jean-Yves Bonnefoy, François Debaene, Sarah Cianférani, Alain Van Dorsselaer, Alain Wagner. Bioconjugate Chem. 2015, 26, 2, 197–200.
Doi: 10.1021/bc500610g
Development of models for prediction of the antioxidant activity of derivatives of natural compounds
Rok Martinčič, Igor Kuzmanovski, Alain Wagner, Marjana Novic. Analytica Chimica Acta. 2015, 868, 23–35.
DOI: 10.1016/j.aca.2015.01.050
Rok Martinčič, Igor Kuzmanovski, Alain Wagner, Marjana Novic. Analytica Chimica Acta. 2015, 868, 23–35.
DOI: 10.1016/j.aca.2015.01.050
2014
4-Halogeno-Sydnones for Fast Strain Promoted Cycloaddition with Cyclooctynes
Lucie Plougastel, Oleksandr Koniev, Simon Specklin, Elodie Decuypere, Christophe Créminon, David-Alexandre Buisson, Alain Wagner, Sergii Kolodych, Frédéric Taran. Chem. Commun. 2014, 50, 66, 9376-9378.
Doi: 10.1039/c4cc03816a
Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe: application to living-cell biothiol imaging
Coraline Egloff, Denis Weltin, C. Calligaro, Michel Mosser, Marc Nothisen, Jean-Serge. Rémy, Alain Wagner. Chem. Commun. 2014, 50, 70, 10049-10051.
Doi: 10.1039/c4cc03548h
Developments in the Field of Bioorthogonal Bond Forming Reactions—Past and Present Trends Mathias King, Alain Wagner. Bioconjugate Chem. 2014, 25, 5, 825–839.
Doi: 10.1021/bc500028d
Copper-Chelating Azides for Efficient Click Conjugation Reactions in Complex Media
Valentina Bevilacqua, Mathias King, Manon Chaumontet, Marc Nothisen, Sandra Gabillet, David Buisson, Céline Puente, Alain Wagner, Frédéric Taran. Angewandte Chemie. 2014, 53 ,23, 5972–5976.
Doi: 10.1002/anie.201310671
Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles
Oleksandr Koniev, Geoffray Leriche, Marc Nothisen, Jean-Serge Remy, Jean-Marc Strub, Christine Schaeffer-Reiss, Alain Van Dorsselaer, Rachid Baati, Alain Wagner. Bioconjugate Chem. 2014, 25, 2, 202–206.
Doi: 10.1021/bc400469d
Probing the catalytic mechanism of bovine CD38/NAD+glycohydrolase by site-directed mutagenesis of key active site residues
Isabelle Kuhn, Esther Kellenberger, Cé, line Cakir-Kiefer, Hélène Muller-Steffner, Francis Schuber. Biochim. Biophys Acta. 2014, 1844, 7, 1317-1331.
Doi: 10.1016/j.bbapap.2014.03.014
Lucie Plougastel, Oleksandr Koniev, Simon Specklin, Elodie Decuypere, Christophe Créminon, David-Alexandre Buisson, Alain Wagner, Sergii Kolodych, Frédéric Taran. Chem. Commun. 2014, 50, 66, 9376-9378.
Doi: 10.1039/c4cc03816a
Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe: application to living-cell biothiol imaging
Coraline Egloff, Denis Weltin, C. Calligaro, Michel Mosser, Marc Nothisen, Jean-Serge. Rémy, Alain Wagner. Chem. Commun. 2014, 50, 70, 10049-10051.
Doi: 10.1039/c4cc03548h
Developments in the Field of Bioorthogonal Bond Forming Reactions—Past and Present Trends Mathias King, Alain Wagner. Bioconjugate Chem. 2014, 25, 5, 825–839.
Doi: 10.1021/bc500028d
Copper-Chelating Azides for Efficient Click Conjugation Reactions in Complex Media
Valentina Bevilacqua, Mathias King, Manon Chaumontet, Marc Nothisen, Sandra Gabillet, David Buisson, Céline Puente, Alain Wagner, Frédéric Taran. Angewandte Chemie. 2014, 53 ,23, 5972–5976.
Doi: 10.1002/anie.201310671
Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles
Oleksandr Koniev, Geoffray Leriche, Marc Nothisen, Jean-Serge Remy, Jean-Marc Strub, Christine Schaeffer-Reiss, Alain Van Dorsselaer, Rachid Baati, Alain Wagner. Bioconjugate Chem. 2014, 25, 2, 202–206.
Doi: 10.1021/bc400469d
Probing the catalytic mechanism of bovine CD38/NAD+glycohydrolase by site-directed mutagenesis of key active site residues
Isabelle Kuhn, Esther Kellenberger, Cé, line Cakir-Kiefer, Hélène Muller-Steffner, Francis Schuber. Biochim. Biophys Acta. 2014, 1844, 7, 1317-1331.
Doi: 10.1016/j.bbapap.2014.03.014
2013
Schistosoma mansoni NAD+ catabolizing enzyme : identification of key residues in catalysis
Isabelle Kuhn, Esther Kellenberger, Francis Schuber, Hélène Muller-Steffner. Biochim. Biophys. Acta. 2013, 1834, 12, 2520-2527.
Doi: 10.1016/j.bbapap.2013.09.002
Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 Trans-infection
Evelyne Schaeffer, Laure Dehuyser, David Sigwalt, Vincent Flacher, Serena Bernacchi, Olivier Chaloin, Jean-Serge Remy, Christophe G. Mueller, Rachid Baati, Alain Wagner, Bioconjugate Chem. 2013, 24, 11, 1813-1823.
Doi: 10.1021/bc4000806
A new series of Cs+, K+ and Na+ chelators: synthesis, kinetics, thermodynamics and modeling
Alexandre Korovitch, Antoine Le Roux, Florent Barbault, Miryana Hémadi, Nguyêt-Thanh Ha-Duong, Claude Lion, Alain Wagner, Jean-Michel El Hage Chahine, Inorganica Chimica Acta, 2013, 394, 45-57.
Doi:10.1016/J.ICA.2012.08.009
Isabelle Kuhn, Esther Kellenberger, Francis Schuber, Hélène Muller-Steffner. Biochim. Biophys. Acta. 2013, 1834, 12, 2520-2527.
Doi: 10.1016/j.bbapap.2013.09.002
Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 Trans-infection
Evelyne Schaeffer, Laure Dehuyser, David Sigwalt, Vincent Flacher, Serena Bernacchi, Olivier Chaloin, Jean-Serge Remy, Christophe G. Mueller, Rachid Baati, Alain Wagner, Bioconjugate Chem. 2013, 24, 11, 1813-1823.
Doi: 10.1021/bc4000806
A new series of Cs+, K+ and Na+ chelators: synthesis, kinetics, thermodynamics and modeling
Alexandre Korovitch, Antoine Le Roux, Florent Barbault, Miryana Hémadi, Nguyêt-Thanh Ha-Duong, Claude Lion, Alain Wagner, Jean-Michel El Hage Chahine, Inorganica Chimica Acta, 2013, 394, 45-57.
Doi:10.1016/J.ICA.2012.08.009
2012
Towards a KCC2 blocker pharmacophore model
Florence Lebon, Cécile Pegurier, Marie Ledecq, Benoit Mathieu, Nathalie Bosman, Anne Frycia, Sébastien Lengelé, Kashinath Dhurke, Ananda Kumar Kanduluru, Stéphane Meunier, Alain Wagner, Christian Wolff, Laurent Provins. Bioorganic & Medicinal Chemistry Letters. 2012, 22, 12, 3978-3982.
Doi: 10.1016/j.bmcl.2012.04.097
First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers
Vincent Lemau de Talancé, Olivier Massinon, Rachid Baati, Alain Wagner, Stéphane P. Vincent. Chemical Communications. 2012, 48, 86, 10684-10686.
Doi: 10.1039/c2cc35386e
New tetramethylthiepinium (TMTI) for copper-free click chemistry
Mathias King, Rachid Baati, Alain Wagner. Chemical Communication, 2012, 48, 74, 9308 – 9309.
Doi: 10.1039/C2CC35034C
Synthesis of Novel Mannoside Glycolipid Conjugates for Inhibition of HIV-1 Trans-Infection
Laure Dehuyser, Evelyne Schaeffer, Olivier Chaloin, Christophe G. Mueller, Rachid Baati, Alain Wagner. Bioconjugate Chem. 2012, 23, 9, 1731–1739.
DOI: 10.1021/bc200644d
Capillary electrophoresis–inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands
Fanny Varenne, Mélanie Bourdillon, Michel Meyer, Yi Lin, Marie Brellier, Rachid Baati, Loïc J. Charbonnière, Alain Wagner, Eric Doris, Frédéric Taran, Agnès Hagège. Journal of Chromatography A. 2012, 1229, 280–287
Doi: 10.1016/j.chroma.2012.01.066
A FRET-based probe with a chemically deactivatable quencher
Geoffray Leriche, Ghyslain Budin, Zeinab Darwich, Denis Weltin, Yves Mély, Andrey S. Klymchenko, Alain Wagner. Chemical Communication 2012, 48, 26, 3224-3226.
DOI: 10.1039/c2cc17542h
Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-Ray structures of its Michaelis Complex and covalently-trapped intermediates
Pascal F. Egea, Hélène Muller-Steffner, Isabelle Kuhn, Céline Cakir-Kiefer, Norman J. Oppenheimer, Robert M. Stroud, Esther Kellenberger, Francis Schuber. PLOS One. 2012, 7, 4, 34918.
Doi: 10.1371/journal.pone.0034918
Mild chemo-selective hydration of terminal alkynes catalyzed by AgSbF6
Mathieu Bui The Thuong, André Mann, Alain Wagner. Chemical Communication, 2012, 48, 3, 434-436.
Doi: 10.1039/c1cc12928g
Trimethoxyarene, a Highly Ionisable Tag for Reaction Analysis by APPI/MS: Exploration of Heterocyclic Synthesis
Mathieu Bui The Thuong, Cédric Catala, Cyril Colas, Christine Schaeffer, Alain Van Dorsselaer, André Mann, Alain Wagner. European Journal of Organic Chemistry, 2012, 2012, 1, 85-92.
Doi: 10.1002/ejoc.201100919
Cleavable linkers in chemical biology
Geoffray Leriche, Louise Chisholm, Alain Wagner. Bioorganic and Medicinal Chemistry. 2012, 20, 2, 571-582.
Doi: 10.1016/j.bmc.2011.07.048
Florence Lebon, Cécile Pegurier, Marie Ledecq, Benoit Mathieu, Nathalie Bosman, Anne Frycia, Sébastien Lengelé, Kashinath Dhurke, Ananda Kumar Kanduluru, Stéphane Meunier, Alain Wagner, Christian Wolff, Laurent Provins. Bioorganic & Medicinal Chemistry Letters. 2012, 22, 12, 3978-3982.
Doi: 10.1016/j.bmcl.2012.04.097
First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers
Vincent Lemau de Talancé, Olivier Massinon, Rachid Baati, Alain Wagner, Stéphane P. Vincent. Chemical Communications. 2012, 48, 86, 10684-10686.
Doi: 10.1039/c2cc35386e
New tetramethylthiepinium (TMTI) for copper-free click chemistry
Mathias King, Rachid Baati, Alain Wagner. Chemical Communication, 2012, 48, 74, 9308 – 9309.
Doi: 10.1039/C2CC35034C
Synthesis of Novel Mannoside Glycolipid Conjugates for Inhibition of HIV-1 Trans-Infection
Laure Dehuyser, Evelyne Schaeffer, Olivier Chaloin, Christophe G. Mueller, Rachid Baati, Alain Wagner. Bioconjugate Chem. 2012, 23, 9, 1731–1739.
DOI: 10.1021/bc200644d
Capillary electrophoresis–inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands
Fanny Varenne, Mélanie Bourdillon, Michel Meyer, Yi Lin, Marie Brellier, Rachid Baati, Loïc J. Charbonnière, Alain Wagner, Eric Doris, Frédéric Taran, Agnès Hagège. Journal of Chromatography A. 2012, 1229, 280–287
Doi: 10.1016/j.chroma.2012.01.066
A FRET-based probe with a chemically deactivatable quencher
Geoffray Leriche, Ghyslain Budin, Zeinab Darwich, Denis Weltin, Yves Mély, Andrey S. Klymchenko, Alain Wagner. Chemical Communication 2012, 48, 26, 3224-3226.
DOI: 10.1039/c2cc17542h
Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-Ray structures of its Michaelis Complex and covalently-trapped intermediates
Pascal F. Egea, Hélène Muller-Steffner, Isabelle Kuhn, Céline Cakir-Kiefer, Norman J. Oppenheimer, Robert M. Stroud, Esther Kellenberger, Francis Schuber. PLOS One. 2012, 7, 4, 34918.
Doi: 10.1371/journal.pone.0034918
Mild chemo-selective hydration of terminal alkynes catalyzed by AgSbF6
Mathieu Bui The Thuong, André Mann, Alain Wagner. Chemical Communication, 2012, 48, 3, 434-436.
Doi: 10.1039/c1cc12928g
Trimethoxyarene, a Highly Ionisable Tag for Reaction Analysis by APPI/MS: Exploration of Heterocyclic Synthesis
Mathieu Bui The Thuong, Cédric Catala, Cyril Colas, Christine Schaeffer, Alain Van Dorsselaer, André Mann, Alain Wagner. European Journal of Organic Chemistry, 2012, 2012, 1, 85-92.
Doi: 10.1002/ejoc.201100919
Cleavable linkers in chemical biology
Geoffray Leriche, Louise Chisholm, Alain Wagner. Bioorganic and Medicinal Chemistry. 2012, 20, 2, 571-582.
Doi: 10.1016/j.bmc.2011.07.048
2011
Flavonoids as inhibitors of human CD38
Esther Kellenberger, Isabelle Kuhn, Francis Schuber, Hélène Muller-Steffner. Bioorg Med Chem Lett. 2011, 21, 13, 3939-3942.
Doi: 10.1016/j.bmcl.2011.05.022
Cationic Polydiacetylene Micelles for Gene Delivery
Emmanuelle Morin, Marc Nothisen, Alain Wagner, Jean-Serge Remy. Bioconjugate 2011, 22, 10, 1916–1923.
Doi: 10.1021/bc200083p
Self-Assembled Nanotubes and Helical Tapes from Diacetylene Nonionic Amphiphiles. Structural Studies before and after Polymerization
Aurélia Perino, Marc Schmutz, Stéphane Meunier, Philippe J. Mésini, Alain Wagner. Langmuir. 2011, 27, 19, 12149–12155.
Doi: 10.1021/la202162q
Structure/function studies of DNA gyrase supramolecular complexes
J. Papillon, N. Potier, C. Crucifix, J. F. Menetret, C. Genet, P. Oudet, A. Wagner, P. Schultz, V. Lamour. FEBS Journal. 2011, 278, 472.
Design and synthesis of new antioxidants predicted by the model developed on a set of pulvinic acid derivatives
Antoire Le Roux, Igor Kuzmanovski, Damien Habrant, Stépahne Meunier, Pierre Bischoff, Brice Nadal, Sophie A.-L. Thetiot-Laurent, Thierry Le Gall, Alain Wagner, Marjana Novic. Journal of Chemical Information and Modeling. 2011, 51, 12, 3050–3059.
Doi: 10.1021/ci200205d
Stereoselective Addition of Grignard Reagents to New P-Chirogenic N-Phosphinoylbenzaldimines: Effect of the Phosphorus Substituents on the Stereoselectivity
Irene Notar Francesco, Coraline Egloff, Alain Wagner, Françoise Colobert. European Journal of Organic Chemistry. 2011, 20-21, 4037-4045.
Doi: 10.1002/ejoc.201100380
Design, synthesis and evaluation of new α-nucleophiles for the hydrolysis of organophosphorus nerve agents: application to the reactivation of phosphorylated acetylcholinesterase
Géraldine Saint-André, Maria Kliachyna, Sanjeevarao Kodepelly, Ludivine Louise-Leriche, Emilie Gillon, Pierre-Yves Renard, Florian Nachon, Rachid Baati, Alain Wagner. Tetrahedron 2011, 67, 34, 6352-6361.
Doi: 10.1016/j.tet.2011.05.130
A Representation to Apply Usual Data Mining Techniques to Chemical Reactions— Illustration on the Rate Constant Of SN2 Reactions in Water
Franck Hoonakker, Nicolas Lachiche, Alexandre Varnek, Alain Wagner. International Journal on Artificial Intelligence Tools, 2011, 20, 02, 253-270.
Doi:10.1142/S0218213011000140
First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase
Guillaume Mercey, Tristan Verdelet, Géraldine Saint-André, Emilie Gillon, Alain Wagner, Rachid Baati, Ludovic Jean, Florian Nachon, Pierre-Yves Renard. Chemical Communication. 2011, 47, 18, 5295-5297.
Doi: 10.1039/c1cc10787a
Programmed Dispersions of MWNTs in Aqueous Media by Coating with Photopolymerizable Synthetic Amphiphiles
Cédric Thauvin, Aurélia Perino, Emmanuel Contal, Emmanuelle Morin, Patrick Schultz, Stéphane Meunier, Alain Wagner. J. Phys. Chem. C. 2011, 115, 15, 7319–7322.
Doi: 10.1021/jp2000464
Synthesis and radioprotective properties of pulvinic acid derivatives
Antoine Le Roux, Stéphane Meunier, Thierry Le Gall, Jean-Marc Denis, Pierre Bischoff, Alain Wagner. ChemMedChem. 2011, 6, 3, 561-569.
Doi: 10.1002/cmdc.201000391
Cationic Cyclization of 2-Alkenyl-1,3-dithiolanes: Diastereoselective Synthesis of trans-Decalins
Sylvie Goncalves, Stefano Santoro, Marc Nicolas, Alain Wagner, Philippe Maillos, Fahmi Himo, Rachid Baati. Journal of Organic Chemistry. 2011, 76, 9, 3274-3285.
Doi: 10.1021/jo2001116
Core functionalization of polydiacetylene micelles by "click" reaction
Emmanuel Contal, Andrey S. Klymchenko, Yves Mély, Stéphane Meunier, Alain Wagner. Soft Matter, 2011, 7, 5, 1648-1650.
Doi: 10.1039/C0SM00943A
Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling
David Díaz Díaz, Emmanuelle Morin, Eva M. Schön, Ghyslain Budin, Alain Wagner, Jean-Serge Remy. Journal of Materials Chemistry. 2011, 21, 641-644.
Doi: 10.1039/C0JM03399E
Structure and behaviour of polydiacetylene-based micelles
Aurélia Perino, Andrey S. Klymchenko, Alexandre Morere, Emmanuel Contal, Alain Rameau, Jean-Michel Guenet, Yves Mély, Alain Wagner. Macromolecular Chemistry and Physics. 2011, 212, 2, 111-117.
Doi: 10.1002/macp.201000459
Esther Kellenberger, Isabelle Kuhn, Francis Schuber, Hélène Muller-Steffner. Bioorg Med Chem Lett. 2011, 21, 13, 3939-3942.
Doi: 10.1016/j.bmcl.2011.05.022
Cationic Polydiacetylene Micelles for Gene Delivery
Emmanuelle Morin, Marc Nothisen, Alain Wagner, Jean-Serge Remy. Bioconjugate 2011, 22, 10, 1916–1923.
Doi: 10.1021/bc200083p
Self-Assembled Nanotubes and Helical Tapes from Diacetylene Nonionic Amphiphiles. Structural Studies before and after Polymerization
Aurélia Perino, Marc Schmutz, Stéphane Meunier, Philippe J. Mésini, Alain Wagner. Langmuir. 2011, 27, 19, 12149–12155.
Doi: 10.1021/la202162q
Structure/function studies of DNA gyrase supramolecular complexes
J. Papillon, N. Potier, C. Crucifix, J. F. Menetret, C. Genet, P. Oudet, A. Wagner, P. Schultz, V. Lamour. FEBS Journal. 2011, 278, 472.
Design and synthesis of new antioxidants predicted by the model developed on a set of pulvinic acid derivatives
Antoire Le Roux, Igor Kuzmanovski, Damien Habrant, Stépahne Meunier, Pierre Bischoff, Brice Nadal, Sophie A.-L. Thetiot-Laurent, Thierry Le Gall, Alain Wagner, Marjana Novic. Journal of Chemical Information and Modeling. 2011, 51, 12, 3050–3059.
Doi: 10.1021/ci200205d
Stereoselective Addition of Grignard Reagents to New P-Chirogenic N-Phosphinoylbenzaldimines: Effect of the Phosphorus Substituents on the Stereoselectivity
Irene Notar Francesco, Coraline Egloff, Alain Wagner, Françoise Colobert. European Journal of Organic Chemistry. 2011, 20-21, 4037-4045.
Doi: 10.1002/ejoc.201100380
Design, synthesis and evaluation of new α-nucleophiles for the hydrolysis of organophosphorus nerve agents: application to the reactivation of phosphorylated acetylcholinesterase
Géraldine Saint-André, Maria Kliachyna, Sanjeevarao Kodepelly, Ludivine Louise-Leriche, Emilie Gillon, Pierre-Yves Renard, Florian Nachon, Rachid Baati, Alain Wagner. Tetrahedron 2011, 67, 34, 6352-6361.
Doi: 10.1016/j.tet.2011.05.130
A Representation to Apply Usual Data Mining Techniques to Chemical Reactions— Illustration on the Rate Constant Of SN2 Reactions in Water
Franck Hoonakker, Nicolas Lachiche, Alexandre Varnek, Alain Wagner. International Journal on Artificial Intelligence Tools, 2011, 20, 02, 253-270.
Doi:10.1142/S0218213011000140
First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase
Guillaume Mercey, Tristan Verdelet, Géraldine Saint-André, Emilie Gillon, Alain Wagner, Rachid Baati, Ludovic Jean, Florian Nachon, Pierre-Yves Renard. Chemical Communication. 2011, 47, 18, 5295-5297.
Doi: 10.1039/c1cc10787a
Programmed Dispersions of MWNTs in Aqueous Media by Coating with Photopolymerizable Synthetic Amphiphiles
Cédric Thauvin, Aurélia Perino, Emmanuel Contal, Emmanuelle Morin, Patrick Schultz, Stéphane Meunier, Alain Wagner. J. Phys. Chem. C. 2011, 115, 15, 7319–7322.
Doi: 10.1021/jp2000464
Synthesis and radioprotective properties of pulvinic acid derivatives
Antoine Le Roux, Stéphane Meunier, Thierry Le Gall, Jean-Marc Denis, Pierre Bischoff, Alain Wagner. ChemMedChem. 2011, 6, 3, 561-569.
Doi: 10.1002/cmdc.201000391
Cationic Cyclization of 2-Alkenyl-1,3-dithiolanes: Diastereoselective Synthesis of trans-Decalins
Sylvie Goncalves, Stefano Santoro, Marc Nicolas, Alain Wagner, Philippe Maillos, Fahmi Himo, Rachid Baati. Journal of Organic Chemistry. 2011, 76, 9, 3274-3285.
Doi: 10.1021/jo2001116
Core functionalization of polydiacetylene micelles by "click" reaction
Emmanuel Contal, Andrey S. Klymchenko, Yves Mély, Stéphane Meunier, Alain Wagner. Soft Matter, 2011, 7, 5, 1648-1650.
Doi: 10.1039/C0SM00943A
Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling
David Díaz Díaz, Emmanuelle Morin, Eva M. Schön, Ghyslain Budin, Alain Wagner, Jean-Serge Remy. Journal of Materials Chemistry. 2011, 21, 641-644.
Doi: 10.1039/C0JM03399E
Structure and behaviour of polydiacetylene-based micelles
Aurélia Perino, Andrey S. Klymchenko, Alexandre Morere, Emmanuel Contal, Alain Rameau, Jean-Michel Guenet, Yves Mély, Alain Wagner. Macromolecular Chemistry and Physics. 2011, 212, 2, 111-117.
Doi: 10.1002/macp.201000459
