2019
Design and evaluation of ionizable peptide amphiphiles for siRNA delivery.
Patrick Neuberg, Alain Wagner, Jean-Serge Remy, Antoine Kichler; Int. J. Pharmaceut., 2019, 566, 141-148.
DOI: 10.1016/j.ijpharm.2019.05.052
Patrick Neuberg, Alain Wagner, Jean-Serge Remy, Antoine Kichler; Int. J. Pharmaceut., 2019, 566, 141-148.
DOI: 10.1016/j.ijpharm.2019.05.052
Sydnone-based turn-on fluorogenic probes for no-wash protein labeling and in-cell imaging.
Lucie Plougastel, Manas R. Pattanayak, Margaux Riomet, Sarah Bregant, Antoine Sallustrau, Marc Nothisen, Alain Wagner, Davide Audisio, Frédéric Taran; Chem. Commun., 2018, 55, 4582-4585. DOI: 10.1039/C9CC01458F
Lucie Plougastel, Manas R. Pattanayak, Margaux Riomet, Sarah Bregant, Antoine Sallustrau, Marc Nothisen, Alain Wagner, Davide Audisio, Frédéric Taran; Chem. Commun., 2018, 55, 4582-4585. DOI: 10.1039/C9CC01458F
2018
Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E-coli YgbP/IspD
Zoljargal Baatarkhuu, Philippe Chaignon, Franck Borel, Jean-Luc Ferrer, Alain Wagner, Myriam Seemann; Scientific Reports, 2018, 8, 17892-17901. DOI: 10.1038/s41598-018-35586-y038/s41598-018-35586-y :10.1038/s41598-018-35586-y
Zoljargal Baatarkhuu, Philippe Chaignon, Franck Borel, Jean-Luc Ferrer, Alain Wagner, Myriam Seemann; Scientific Reports, 2018, 8, 17892-17901. DOI: 10.1038/s41598-018-35586-y038/s41598-018-35586-y :10.1038/s41598-018-35586-y
Co-delivery of anti-PLK-1 si RNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing
Manon Ripoll, Marie Pierdant, Patrick Neuberg, Dominique Bagnard, Alain Wagner, Antoine Kichler, Jean-Serge Remy; RSC Advances, 2018, 8, 20758-20763. DOI: 10.1039/c8ra03375g
Manon Ripoll, Marie Pierdant, Patrick Neuberg, Dominique Bagnard, Alain Wagner, Antoine Kichler, Jean-Serge Remy; RSC Advances, 2018, 8, 20758-20763. DOI: 10.1039/c8ra03375g
Expedient synthesis of trifunctional oligoethyleneglycol-amine linkers and their use in the preparation of PEG-based branched platforms
Sylvain Ursuegui, Jérémy P. Schneider, Claire Imbs, Florian Lauvoisard, Marta Dudek, Michel Mosser, Alain Wagner; Organic and Biomolecular Chemistry, 2018, In press
DOI: 10.1039/c8ob02097c
Sylvain Ursuegui, Jérémy P. Schneider, Claire Imbs, Florian Lauvoisard, Marta Dudek, Michel Mosser, Alain Wagner; Organic and Biomolecular Chemistry, 2018, In press
DOI: 10.1039/c8ob02097c
Recent, non-classical, approaches to antibody lysine modification
Guilhem Chaubet, Fabien Thoreau, Alain Wagner; Drug Discovery Today: Technologies, 2018, In press
Guilhem Chaubet, Fabien Thoreau, Alain Wagner; Drug Discovery Today: Technologies, 2018, In press
Reduction Inhibition of dengue virus infection by mannoside glycolipid conjugates
Evelune Schaeffera, Vincent Flachera, Patrick Neuberg, Astrid Hostea, Adrien Bruleferta, Jean-Daniel Faunja, Alain Wagner, Christopher G. Muellera; Antiviral Research, 2018, 154, 116-123
Evelune Schaeffera, Vincent Flachera, Patrick Neuberg, Astrid Hostea, Adrien Bruleferta, Jean-Daniel Faunja, Alain Wagner, Christopher G. Muellera; Antiviral Research, 2018, 154, 116-123
Reduction–rebridging strategy for the preparation of ADPN-based antibody–drug conjugates
Oleksandr Koniev, Igor Dovgan, Brigitte Renoux, Anthony Ehkirch, Jitka Eberova, Sarah Cianférani, Sergii Kolodych, Sébastien Papot and Alain Wagner, Med. Chem. Commun., 2018, DOI: 10.1039/C8MD00141C
Oleksandr Koniev, Igor Dovgan, Brigitte Renoux, Anthony Ehkirch, Jitka Eberova, Sarah Cianférani, Sergii Kolodych, Sébastien Papot and Alain Wagner, Med. Chem. Commun., 2018, DOI: 10.1039/C8MD00141C
Arginine-Selective Bioconjugation with 4-Azidophenyl glyoxal: Application to the single and Dual Functionalisation of Native Antibody
Igor Dovgan, Stéphane Erb, Steve Hessman, Sylvain Ursuegui, Chloé Michel, Christian Muller, Guilhem Chaubet, Sarah Cianférani and Alain Wagner, Organic & Biomolecular Chemistry, 2018, DOI: 10.1039/C7OB02844J
Igor Dovgan, Stéphane Erb, Steve Hessman, Sylvain Ursuegui, Chloé Michel, Christian Muller, Guilhem Chaubet, Sarah Cianférani and Alain Wagner, Organic & Biomolecular Chemistry, 2018, DOI: 10.1039/C7OB02844J
Polydiacetylenic Nanofibers as New siRNA Vehicles for in vitro and in vivo Delivery
E P. Neuberg, I. Hamaidi, D. Danilin, M. Ripoll, V. Lindner, M. Nothisen, A. Wagner, A. Kichler, T. Massfelder and J.-D. Remy, Nanoscale, 2018, DOI: 10.1039/C7NR09202D
E P. Neuberg, I. Hamaidi, D. Danilin, M. Ripoll, V. Lindner, M. Nothisen, A. Wagner, A. Kichler, T. Massfelder and J.-D. Remy, Nanoscale, 2018, DOI: 10.1039/C7NR09202D
2017
Structural Investigation of Cyclo-dioxo Maleimide Cross-linkers for Acid and Serum Stability
Elisabetta Tobaldi, Igor Dovgan, Michel Mosser, Jean-Michel Becht, Alain Wagner, Organic & Biomolecular Chemistry, 2017, 15, 9305-9310
Elisabetta Tobaldi, Igor Dovgan, Michel Mosser, Jean-Michel Becht, Alain Wagner, Organic & Biomolecular Chemistry, 2017, 15, 9305-9310
Discovery of New Click and Release Reactions by Screening of Mesoionics and Cycloalkynes Combinations
Frédéric Taran, Sabrina Bernard, Davide Audisio, Riomet Margaux, Sarah Bregant, Antoine Sallustrau, Lucie Plougastel, Elodie Decuypere, Sandra Gabillet, Ramar Arun Kumar, Jijy Elyian, Minh Nguyet Trinh, Oleksandr Koniev, Alain Wagner, Sergii Kolodych, Angewandte Chemie International Edition, 2017, 56, 15612–15616
Frédéric Taran, Sabrina Bernard, Davide Audisio, Riomet Margaux, Sarah Bregant, Antoine Sallustrau, Lucie Plougastel, Elodie Decuypere, Sandra Gabillet, Ramar Arun Kumar, Jijy Elyian, Minh Nguyet Trinh, Oleksandr Koniev, Alain Wagner, Sergii Kolodych, Angewandte Chemie International Edition, 2017, 56, 15612–15616
Development and evaluation of β-galactosidase-sensitive antibody-drug conjugates Kolodych, S., Michel, C., Delacroix, S., Koniev, O., Ehkirch, A., Eberova, J., Cianférani, S., Renoux, B., Krezel, W., Poinot, P., Muller, C. D., Papot, S., Wagner, A., European Journal of Medicinal Chemistry, 2017, 142, 376-382
An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin S. Ursuegui, M. Recher, W. Krężel, A. Wagner. Nature Comm., 2017, 8, 15242
Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy. I. Dovgan, S. Ursuegui, S. Erb, C. Michel, S. Kolodych, S. Cianférani, A. Wagner. Bioconjugate Chem., 2017, 10.1021/acs.bioconjchem.7b00141
2016
pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery. M. Ripoll, P. Neuberg, A. Kichler, N. Tounsi, A. Wagner, J.S.Remy. ACS Appl Mater Interfaces, 2016, 8, 30665–30670
Copper-free click chemistry for microdroplet's W/O interface engineering. S. Ursuegui, M. Mosser, A. Wagner. RSC Advances, 2016, 6, 94942 – 94948
Ultrafast Click Chemistry with Fluorosydnones. H. Liu, D. Audisio, L. Plougastel, E. Decuypere, D.-A. Buisson, O. Koniev, S. Kolodych, A. Wagner, M. Elhabiri, A. Krzyczmonik, S. Forsback, O. Solin, V. Gouverneur, F. Taran. Angewandte Chemie Int. Ed., 2016, 55, 12073 –12077
2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation. I. Dovgan, S. Kolodych, O. Koniev, A. Wagner. Nature Scientific Report, 2016, 6, 30835-30840
Palladium Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature. R. Ahmed Atto Al-Shuaeeb, S. Kolodych, O. Koniev, S. Delacroix, S. Erb, S. Nicolaÿ, J-C. Cintrat, J.-D. Brion, S. Cianférani, M. Alami, A. Wagner, S. Messaoudi. Chem. Eur. J., 2016, 22, 11365 – 11370
From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release. S. A. Jacques, G. Leriche, M. Mosser, M. Nothisen, C. D. Muller, J.S. Remy, A. Wagner. Org. Biomol. Chem., 2016, 14, 4794–4803
2015
Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation.
V. Flacher, P. Neuberg, F. Point, F. Daubeuf, Q. Muller, D. Sigwalt, J.D. Fauny, J.S. Remy, N. Frossard, A. Wagner, C. G. Mueller, E. Schaeffer ACS Chem. Biol., 2015, 10, 2697–2705
V. Flacher, P. Neuberg, F. Point, F. Daubeuf, Q. Muller, D. Sigwalt, J.D. Fauny, J.S. Remy, N. Frossard, A. Wagner, C. G. Mueller, E. Schaeffer ACS Chem. Biol., 2015, 10, 2697–2705
MAPN: New Reagent for Kinetically Resolved Thiol-to-Thiol Coupling. O. Koniev, S. Kolodych, Z. Baatarkhuu, J.Y. Bonnefoy, A. Wagner. Bioconjugate Chem., 2015, 26, 1863–1867
Spiro Di-orthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release. G. Leriche, S. A. Jacques, M. Nothisen, N. Baumlin, C. D. Muller, D. Bagnard, J.S. Remy, A. Wagner, Bioconjugate Chem., 2015, 26, 1461-1465
Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties. P. Neuberg, A. Périno, E. Morin-Picardat, N. Anton, Z. Darwich, D. Weltin, Y. Mely, A. S. Klymchenko, J.S. Remy, A. Wagner, Chem. Commun., 2015, 51, 11595-11598
Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation. O. Koniev, A. Wagner, Chem. Soc. Rev., 2015, 44, 5495-5551
Discovery of potent inhibitors of Schistosoma mansoni NAD+ catabolizing enzyme. S. A. Jacques, I. Kuhn, O. Koniev, F. Schuber, F. E. Lund, A. Wagner, H. Muller-Steffner, E. Kellenberger, J. Med. Chem., 2015, 58, 3582–3592
CBTF: New Amine-to-Thiol Coupling Reagent for Preparation of Antibody Conjugates with Increased Plasma Stability. S. Kolodych, O. Koniev, Z. Baatarkhuu, J.Y. Bonnefoy, F. Debaene, S. Cianférani, A. Van Dorsselaer, A. Wagner. Bioconjugate Chem., 2015, 26, 197–200.
Development of models for prediction of the antioxidant activity of derivatives of natural compounds. R. Martinčič; I. Kuzmanovski, A. Wagner, M. Novic. Analytica Chimica Acta. 2015, 868, 23–35
2014
4-Halogeno-Sydnones for Fast Strain Promoted Cycloaddition with Cyclooctynes. L. Plougastel, O. Koniev, S. Specklin, E. Decuypere, C. Créminon, D. Buisson, A. Wagner, S. Kolodych, F. Taran. Chem Commun, 2014, 50, 9376-9378.
Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe: application to living-cell biothiol imaging. C. Egloff, D. Weltin, C. Calligaro, M. Mosser, M. Nothisen, J.S. Rémy, A. Wagner. Chem. Commun., 2014, 50, 10049-10051
Developments in the Field of Bioorthogonal Bond Forming Reactions—Past and Present Trends. M. King, A. Wagner. Bioconjugate Chem., 2014, 25, 825–839
Copper-Chelating Azides for Efficient Click Conjugation Reactions in Complex Media. V. Bevilacqua, M. King, M. Chaumontet, M. Nothisen, S. Gabillet, D. Buisson, C. Puente, A. Wagner, F. Taran. Angewandte Chemie, 2014, 126, 5982–5986
Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles. O. Koniev, G. Leriche, M. Nothisen, J.S. Remy, J.M. Strub, C. Schaeffer-Reiss, A. Van Dorsselaer, R. Baat, A. Wagner. Bioconjugate Chem, 2014, 25, 202–206
Probing the catalytic mechanism of bovine CD38/NAD+glycohydrolase by site-directed mutagenesis of key active site residues. Kuhn, I., Kellenberger, E., Cakir-Kiefer, C., Muller-Steffner, H., Schuber, F. Biochim. Biophys Acta, 2014, 1317-1331
Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe: application to living-cell biothiol imaging. C. Egloff, D. Weltin, C. Calligaro, M. Mosser, M. Nothisen, J.S. Rémy, A. Wagner. Chem. Commun., 2014, 50, 10049-10051
Developments in the Field of Bioorthogonal Bond Forming Reactions—Past and Present Trends. M. King, A. Wagner. Bioconjugate Chem., 2014, 25, 825–839
Copper-Chelating Azides for Efficient Click Conjugation Reactions in Complex Media. V. Bevilacqua, M. King, M. Chaumontet, M. Nothisen, S. Gabillet, D. Buisson, C. Puente, A. Wagner, F. Taran. Angewandte Chemie, 2014, 126, 5982–5986
Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles. O. Koniev, G. Leriche, M. Nothisen, J.S. Remy, J.M. Strub, C. Schaeffer-Reiss, A. Van Dorsselaer, R. Baat, A. Wagner. Bioconjugate Chem, 2014, 25, 202–206
Probing the catalytic mechanism of bovine CD38/NAD+glycohydrolase by site-directed mutagenesis of key active site residues. Kuhn, I., Kellenberger, E., Cakir-Kiefer, C., Muller-Steffner, H., Schuber, F. Biochim. Biophys Acta, 2014, 1317-1331
2013
Schistosoma mansoni NAD+ catabolizing enzyme : identification of key residues in catalysis. I. Kuhn, E. Kellenberger, F. Schuber, H. Muller-Steffner. Biochim. Biophys. Acta 2013, 1834, 2520-2527
Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 Trans-infection. E. Schaeffer, L. Dehuyser, D. Sigwalt, V. Flacher, S. Bernacchi, O. Chaloin, J.S. Remy, C. G. Mueller, R. Baati, A. Wagner, Bioconjugate Chem., 2013, 24, 1813-1823
A new series of Cs+, K+ and Na+ chelators: synthesis, kinetics, thermodynamics and modeling. A. Korovitch, A. Le Roux, F. Barbault, M. Hemadi, N.T. Ha-Duong, C. Lion, A. Wagner, J.M. El Hage Chahine, Inorganica Chimica Acta, 2013, 394, 45-57
Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 Trans-infection. E. Schaeffer, L. Dehuyser, D. Sigwalt, V. Flacher, S. Bernacchi, O. Chaloin, J.S. Remy, C. G. Mueller, R. Baati, A. Wagner, Bioconjugate Chem., 2013, 24, 1813-1823
A new series of Cs+, K+ and Na+ chelators: synthesis, kinetics, thermodynamics and modeling. A. Korovitch, A. Le Roux, F. Barbault, M. Hemadi, N.T. Ha-Duong, C. Lion, A. Wagner, J.M. El Hage Chahine, Inorganica Chimica Acta, 2013, 394, 45-57
2012
Towards a KCC2 blocker pharmacophore model. F. Lebon, C. Pegurier, M. M. Ledecq ; M. Benoit, N. Bosman, A. Frycia, S. Lengele, K. Dhurke, Ananda Kumar Kanduluru, S. Meunier, A. Wagner, L. Provins. Bioorganic & Medicinal Chemistry Letters, 2012, 22, 3978-3982
First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers. V. Lemau de Talance, O. Massinon, R. Baati, A. Wagner, S. P. Vincent. Chemical Communications 2012, 48(86), 10684-10686
New tetramethylthiepinium (TMTI) for copper-free click chemistry. M. King, R. Baati, A. Wagner. Chemical Communication, 2012, 48, 9308 – 9309
Synthesis of Novel Mannoside Glycolipid Conjugates for Inhibition of HIV-1 Trans-Infection. L. Dehuyser, E. Schaeffer, O. Chaloin, C. G. Mueller, R. Baati, A. Wagner. Bioconjugate Chem., 2012, 23, 1731–1739
Capillary electrophoresis–inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands. F. Varenne, M. Bourdillon, M. Meyer, Y. Lin, M. Brellier, R. Baati, L. J. Charbonnière, A. Wagner, E. Doris, F. Taran, A. Hagège. Journal of Chromatography A, 2012, 1229, 280–287
A FRET-based probe with a chemically deactivatable quencher. Geoffray Leriche, Ghyslain Budin, Zeinab Darwich, Denis Weltin, Yves Mély, Andrey S. Klymchenko, Alain Wagner. Chemical Communication 2012, 48, 3224-3226
Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-Ray structures of its Michaelis Complex and covalently-trapped intermediates. P. Egea, H. Muller-Steffner, H., Kuhn, I., Cakir-Kiefer, C., Oppenheimer,N.J., Stroud, R.M., Kellenberger, E., Schuber, F. PLOS One, 2012, 7, 34918
Mild chemo-selective hydration of terminal alkynes catalyzed by AgSbF6. M. Bui, A. Mann, A. Wagner. Chemical Communication, 2012, 48, 434-436
Trimethoxyarene, a Highly Ionisable Tag for Reaction Analysis by APPI/MS: Exploration of Heterocyclic Synthesis. M. Bui, T. Thuong, C. Catala, C. Colas, C. Schaeffer, A. Van Dorsselaer, A. Mann, A. Wagner. European Journal of Organic Chemistry, 2012, 85-92
Cleavable linkers in chemical biology. G. Leriche, L. Chisholm, A. Wagner. Bioorganic and Medicinal Chemistry, 2012, 20,571-582
First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers. V. Lemau de Talance, O. Massinon, R. Baati, A. Wagner, S. P. Vincent. Chemical Communications 2012, 48(86), 10684-10686
New tetramethylthiepinium (TMTI) for copper-free click chemistry. M. King, R. Baati, A. Wagner. Chemical Communication, 2012, 48, 9308 – 9309
Synthesis of Novel Mannoside Glycolipid Conjugates for Inhibition of HIV-1 Trans-Infection. L. Dehuyser, E. Schaeffer, O. Chaloin, C. G. Mueller, R. Baati, A. Wagner. Bioconjugate Chem., 2012, 23, 1731–1739
Capillary electrophoresis–inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands. F. Varenne, M. Bourdillon, M. Meyer, Y. Lin, M. Brellier, R. Baati, L. J. Charbonnière, A. Wagner, E. Doris, F. Taran, A. Hagège. Journal of Chromatography A, 2012, 1229, 280–287
A FRET-based probe with a chemically deactivatable quencher. Geoffray Leriche, Ghyslain Budin, Zeinab Darwich, Denis Weltin, Yves Mély, Andrey S. Klymchenko, Alain Wagner. Chemical Communication 2012, 48, 3224-3226
Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-Ray structures of its Michaelis Complex and covalently-trapped intermediates. P. Egea, H. Muller-Steffner, H., Kuhn, I., Cakir-Kiefer, C., Oppenheimer,N.J., Stroud, R.M., Kellenberger, E., Schuber, F. PLOS One, 2012, 7, 34918
Mild chemo-selective hydration of terminal alkynes catalyzed by AgSbF6. M. Bui, A. Mann, A. Wagner. Chemical Communication, 2012, 48, 434-436
Trimethoxyarene, a Highly Ionisable Tag for Reaction Analysis by APPI/MS: Exploration of Heterocyclic Synthesis. M. Bui, T. Thuong, C. Catala, C. Colas, C. Schaeffer, A. Van Dorsselaer, A. Mann, A. Wagner. European Journal of Organic Chemistry, 2012, 85-92
Cleavable linkers in chemical biology. G. Leriche, L. Chisholm, A. Wagner. Bioorganic and Medicinal Chemistry, 2012, 20,571-582
2011
Flavonoids as inhibitors of human CD38. E. Kellenberger, I. Kuhn, F. Schuber, H. Muller-Steffner. Bioorg Med Chem Lett, 2011, 21, 3939-3942
Cationic Polydiacetylene Micelles for Gene Delivery. E. Morin, M. Nothisen, A. Wagner, J.S. Remy. Bioconjugate 2011, 22, 1916–1923
Self-Assembled Nanotubes and Helical Tapes from Diacetylene Nonionic Amphiphiles. Structural Studies before and after Polymerization. A. Perino, M. Schmutz, S. Meunier, P. Mésini, A. Wagner. Langmuir, 2011, 27, 12149–12155
Structure/function studies of DNA gyrase supramolecular complexes. J. Papillon, N. Potier, C. Crucifix, J. F. Menetret, C. Genet, P. Oudet, A. Wagner, P. Schultz, V. Lamour. FEBS Journal, 2011, 278, 472
Design and synthesis of new antioxidants predicted by the model developed on a set of pulvinic acid derivatives. A. Le Roux, I. Kuzmanovski, D. Habrant, S. Meunier, P. Bischoff, S. Thetiot-Laurent, T. Le Gall, A. Wagner, M. Novic. Journal of Chemical Information and Modeling, 2011, 51, 3050–3059
Stereoselective Addition of Grignard Reagents to New P-Chirogenic N-Phosphinoylbenzaldimines: Effect of the Phosphorus Substituents on the Stereoselectivity. I. N. Francesco, C. Egloff, A. Wagner, F. Colobert. European Journal of Organic Chemistry, 2011, 20-21
Design, synthesis and evaluation of new α-nucleophiles for the hydrolysis of organophosphorus nerve agents: application to the reactivation of phosphorylated acetylcholinesterase. G. Saint-Andre, M. Kliachyna, S. Kodepelly, L. Louise-Leriche, E. Gillon, P.Y. Renard, F. Nachon, R. Baati, A. Wagner. Tetrahedron 2011, 67, 6352-6361
A Representation to Apply Usual Data Mining Techniques to Chemical Reactions— Illustration on the Rate Constant Of SN2 Reactions in Water. F. Hoonakker, A. Varnek, N. Lachiche, A. Wagner. International Journal on Artificial Intelligence Tools, 2011, 20, 253-270
First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase. G. Mercey, T. Verdelet, G. Saint-André, E. Gillon, A. Wagner, R. Baati, L. Jean, F. Nachon, P.Y. Renard. Chemical Communication, 2011, 47, 5295-5297
Programmed Dispersions of MWNTs in Aqueous Media by Coating with Photopolymerizable Synthetic Amphiphiles. C. Thauvin, A. Perino, E. Contal, E. Morin, P. Schultz, S. Meunier, A. Wagner. J. Phys. Chem. C, 2011, 115, 7319–7322
Synthesis and radioprotective properties of pulvinic acid derivatives. A. Le Roux, S. Meunier, T. Le Gall, J.M. Denis, P. Bischoff, A. Wagner. ChemMedChem., 2011, 6, 561-569
Cationic Cyclization of 2-Alkenyl-1,3-dithiolanes: Diastereoselective Synthesis of trans-Decalins. S. Goncalves, S. Santoro, M. Nicolas, A. Wagner, P. Maillos, F. Himo, R. Baati. Journal of Organic Chemistry, 2011, 76, 3274-3285
Core functionalization of polydiacetylene micelles by "click" reaction. E. Contal, A. S. Klymchenko, Y. Mely, S. Meunier, A. Wagner. Soft Matter, 2011, 7, 1648-1650
Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling. D. D. Díaz, E. Morin, E. M. Schön, G. Budin, A. Wagner, J.S. Remy. Journal of Materials Chemistry, 2011, 21, 641-644
Structure and behaviour of polydiacetylene-based micelles. A. Perino, A. S. Klymchenko, A. Morere, E. Contal, A. Rameau, J.M. Guenet, Y. Mély, A. Wagner, Macromolecular Chemistry and Physics 2011, 212, 111-117
Cationic Polydiacetylene Micelles for Gene Delivery. E. Morin, M. Nothisen, A. Wagner, J.S. Remy. Bioconjugate 2011, 22, 1916–1923
Self-Assembled Nanotubes and Helical Tapes from Diacetylene Nonionic Amphiphiles. Structural Studies before and after Polymerization. A. Perino, M. Schmutz, S. Meunier, P. Mésini, A. Wagner. Langmuir, 2011, 27, 12149–12155
Structure/function studies of DNA gyrase supramolecular complexes. J. Papillon, N. Potier, C. Crucifix, J. F. Menetret, C. Genet, P. Oudet, A. Wagner, P. Schultz, V. Lamour. FEBS Journal, 2011, 278, 472
Design and synthesis of new antioxidants predicted by the model developed on a set of pulvinic acid derivatives. A. Le Roux, I. Kuzmanovski, D. Habrant, S. Meunier, P. Bischoff, S. Thetiot-Laurent, T. Le Gall, A. Wagner, M. Novic. Journal of Chemical Information and Modeling, 2011, 51, 3050–3059
Stereoselective Addition of Grignard Reagents to New P-Chirogenic N-Phosphinoylbenzaldimines: Effect of the Phosphorus Substituents on the Stereoselectivity. I. N. Francesco, C. Egloff, A. Wagner, F. Colobert. European Journal of Organic Chemistry, 2011, 20-21
Design, synthesis and evaluation of new α-nucleophiles for the hydrolysis of organophosphorus nerve agents: application to the reactivation of phosphorylated acetylcholinesterase. G. Saint-Andre, M. Kliachyna, S. Kodepelly, L. Louise-Leriche, E. Gillon, P.Y. Renard, F. Nachon, R. Baati, A. Wagner. Tetrahedron 2011, 67, 6352-6361
A Representation to Apply Usual Data Mining Techniques to Chemical Reactions— Illustration on the Rate Constant Of SN2 Reactions in Water. F. Hoonakker, A. Varnek, N. Lachiche, A. Wagner. International Journal on Artificial Intelligence Tools, 2011, 20, 253-270
First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase. G. Mercey, T. Verdelet, G. Saint-André, E. Gillon, A. Wagner, R. Baati, L. Jean, F. Nachon, P.Y. Renard. Chemical Communication, 2011, 47, 5295-5297
Programmed Dispersions of MWNTs in Aqueous Media by Coating with Photopolymerizable Synthetic Amphiphiles. C. Thauvin, A. Perino, E. Contal, E. Morin, P. Schultz, S. Meunier, A. Wagner. J. Phys. Chem. C, 2011, 115, 7319–7322
Synthesis and radioprotective properties of pulvinic acid derivatives. A. Le Roux, S. Meunier, T. Le Gall, J.M. Denis, P. Bischoff, A. Wagner. ChemMedChem., 2011, 6, 561-569
Cationic Cyclization of 2-Alkenyl-1,3-dithiolanes: Diastereoselective Synthesis of trans-Decalins. S. Goncalves, S. Santoro, M. Nicolas, A. Wagner, P. Maillos, F. Himo, R. Baati. Journal of Organic Chemistry, 2011, 76, 3274-3285
Core functionalization of polydiacetylene micelles by "click" reaction. E. Contal, A. S. Klymchenko, Y. Mely, S. Meunier, A. Wagner. Soft Matter, 2011, 7, 1648-1650
Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling. D. D. Díaz, E. Morin, E. M. Schön, G. Budin, A. Wagner, J.S. Remy. Journal of Materials Chemistry, 2011, 21, 641-644
Structure and behaviour of polydiacetylene-based micelles. A. Perino, A. S. Klymchenko, A. Morere, E. Contal, A. Rameau, J.M. Guenet, Y. Mély, A. Wagner, Macromolecular Chemistry and Physics 2011, 212, 111-117
